Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma

The intratumor microenvironment generates phenotypically distinct but interconvertible malignant cell subpopulations that fuel metastatic spread and therapeutic resistance. Whether different microenvironmental cues impose invasive or therapy-resistant phenotypes via a common mechanism is unknown. In...

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Detalles Bibliográficos
Autores principales: Falletta, Paola, Sanchez-del-Campo, Luis, Chauhan, Jagat, Effern, Maike, Kenyon, Amy, Kershaw, Christopher J., Siddaway, Robert, Lisle, Richard, Freter, Rasmus, Daniels, Matthew J., Lu, Xin, Tüting, Thomas, Middleton, Mark, Buffa, Francesca M., Willis, Anne E., Pavitt, Graham, Ronai, Ze'ev A., Sauka-Spengler, Tatjana, Hölzel, Michael, Goding, Colin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287109/
https://www.ncbi.nlm.nih.gov/pubmed/28096186
http://dx.doi.org/10.1101/gad.290940.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287109/
https://www.ncbi.nlm.nih.gov/pubmed/28096186
http://dx.doi.org/10.1101/gad.290940.116

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