The PIDDosome activates p53 in response to supernumerary centrosomes

Centrosomes, the main microtubule-organizing centers in animal cells, are replicated exactly once during the cell division cycle to form the poles of the mitotic spindle. Supernumerary centrosomes can lead to aberrant cell division and have been causally linked to chromosomal instability and cancer....

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Detalles Bibliográficos
Autores principales: Fava, Luca L., Schuler, Fabian, Sladky, Valentina, Haschka, Manuel D., Soratroi, Claudia, Eiterer, Lisa, Demetz, Egon, Weiss, Guenter, Geley, Stephan, Nigg, Erich A., Villunger, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287111/
https://www.ncbi.nlm.nih.gov/pubmed/28130345
http://dx.doi.org/10.1101/gad.289728.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287111/
https://www.ncbi.nlm.nih.gov/pubmed/28130345
http://dx.doi.org/10.1101/gad.289728.116

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