Cargando…

The human initiator is a distinct and abundant element that is precisely positioned in focused core promoters

DNA sequence signals in the core promoter, such as the initiator (Inr), direct transcription initiation by RNA polymerase II. Here we show that the human Inr has the consensus of BBCA(+1)BW at focused promoters in which transcription initiates at a single site or a narrow cluster of sites. The analy...

Descripción completa

Detalles Bibliográficos
Autores principales: Vo ngoc, Long, Cassidy, California Jack, Huang, Cassidy Yunjing, Duttke, Sascha H.C., Kadonaga, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287114/
https://www.ncbi.nlm.nih.gov/pubmed/28108474
http://dx.doi.org/10.1101/gad.293837.116