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APOBEC3A/B-induced mutagenesis is responsible for 20% of heritable mutations in the TpCpW context
APOBEC3A/B cytidine deaminase is responsible for the majority of cancerous mutations in a large fraction of cancer samples. However, its role in heritable mutagenesis remains very poorly understood. Recent studies have demonstrated that both in yeast and in human cancerous cells, most APOBEC3A/B-ind...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287224/ https://www.ncbi.nlm.nih.gov/pubmed/27940951 http://dx.doi.org/10.1101/gr.210336.116 |