Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes

Blood glucose levels are tightly controlled by the coordinated action of at least four cell types constituting pancreatic islets. Changes in the proportion and/or function of these cells are associated with genetic and molecular pathophysiology of monogenic, type 1, and type 2 (T2D) diabetes. Cellul...

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Detalles Bibliográficos
Autores principales: Lawlor, Nathan, George, Joshy, Bolisetty, Mohan, Kursawe, Romy, Sun, Lili, Sivakamasundari, V., Kycia, Ina, Robson, Paul, Stitzel, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287227/
https://www.ncbi.nlm.nih.gov/pubmed/27864352
http://dx.doi.org/10.1101/gr.212720.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287227/
https://www.ncbi.nlm.nih.gov/pubmed/27864352
http://dx.doi.org/10.1101/gr.212720.116

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