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Characterization of hundreds of regulatory landscapes in developing limbs reveals two regimes of chromatin folding

Complex regulatory landscapes control the pleiotropic transcriptional activities of developmental genes. For most genes, the number, location, and dynamics of their associated regulatory elements are unknown. In this work, we characterized the three-dimensional chromatin microarchitecture and regula...

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Detalles Bibliográficos
Autores principales: Andrey, Guillaume, Schöpflin, Robert, Jerković, Ivana, Heinrich, Verena, Ibrahim, Daniel M., Paliou, Christina, Hochradel, Myriam, Timmermann, Bernd, Haas, Stefan, Vingron, Martin, Mundlos, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287228/
https://www.ncbi.nlm.nih.gov/pubmed/27923844
http://dx.doi.org/10.1101/gr.213066.116