Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes

Transcriptional enhancers are critical for maintaining cell-type–specific gene expression and driving cell fate changes during development. Highly transcribed genes are often associated with a cluster of individual enhancers such as those found in locus control regions. Recently, these have been ter...

Descripción completa

Detalles Bibliográficos
Autores principales: Moorthy, Sakthi D., Davidson, Scott, Shchuka, Virlana M., Singh, Gurdeep, Malek-Gilani, Nakisa, Langroudi, Lida, Martchenko, Alexandre, So, Vincent, Macpherson, Neil N., Mitchell, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287230/
https://www.ncbi.nlm.nih.gov/pubmed/27895109
http://dx.doi.org/10.1101/gr.210930.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287230/
https://www.ncbi.nlm.nih.gov/pubmed/27895109
http://dx.doi.org/10.1101/gr.210930.116

Ejemplares similares