Drug regimens identified and optimized by output-driven platform markedly reduce tuberculosis treatment time

The current drug regimens for treating tuberculosis are lengthy and onerous, and hence complicated by poor adherence leading to drug resistance and disease relapse. Previously, using an output-driven optimization platform and an in vitro macrophage model of Mycobacterium tuberculosis infection, we i...

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Detalles Bibliográficos
Autores principales: Lee, Bai-Yu, Clemens, Daniel L., Silva, Aleidy, Dillon, Barbara Jane, Masleša-Galić, Saša, Nava, Susana, Ding, Xianting, Ho, Chih-Ming, Horwitz, Marcus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287291/
https://www.ncbi.nlm.nih.gov/pubmed/28117835
http://dx.doi.org/10.1038/ncomms14183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287291/
https://www.ncbi.nlm.nih.gov/pubmed/28117835
http://dx.doi.org/10.1038/ncomms14183

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