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FOXC1 is involved in ERα silencing by counteracting GATA3 binding and is implicated in endocrine resistance
Estrogen receptor-α (ERα) mediates the essential biological function of estrogen in breast development and tumorigenesis. Multiple mechanisms, including pioneer factors, coregulators, and epigenetic modifications have been identified as regulators of ERα signaling in breast cancer. However, previous...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287293/ https://www.ncbi.nlm.nih.gov/pubmed/27041579 http://dx.doi.org/10.1038/onc.2016.78 |