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FOXC1 is involved in ERα silencing by counteracting GATA3 binding and is implicated in endocrine resistance

Estrogen receptor-α (ERα) mediates the essential biological function of estrogen in breast development and tumorigenesis. Multiple mechanisms, including pioneer factors, coregulators, and epigenetic modifications have been identified as regulators of ERα signaling in breast cancer. However, previous...

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Detalles Bibliográficos
Autores principales: Yu-Rice, Yi, Jin, Yanli, Han, Bingchen, Qu, Ying, Johnson, Jeffrey, Watanabe, Takaaki, Cheng, Long, Deng, Nan, Tanaka, Hisashi, Gao, Bowen, Liu, Zhenqiu, Sun, Zhijun, Bose, Shikha, Giuliano, Armando E., Cui, Xiaojiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287293/
https://www.ncbi.nlm.nih.gov/pubmed/27041579
http://dx.doi.org/10.1038/onc.2016.78