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Reed-Sternberg cells in Hodgkin's lymphoma present features of cellular senescence

Hodgkin's Lymphoma (HL) is one of the most prevailing malignancies in young adults. Reed–Sternberg (RS) cells in HL have distinctive large cell morphology, are characteristic of the disease and their presence is essential for diagnosis. Enlarged cells are one of the hallmarks of senescence, but...

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Detalles Bibliográficos
Autores principales: Gopas, J, Stern, E, Zurgil, U, Ozer, J, Ben-Ari, A, Shubinsky, G, Braiman, A, Sinay, R, Ezratty, J, Dronov, V, Balachandran, S, Benharroch, D, Livneh, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287295/
https://www.ncbi.nlm.nih.gov/pubmed/27831553
http://dx.doi.org/10.1038/cddis.2016.185