Cargando…

Reed-Sternberg cells in Hodgkin's lymphoma present features of cellular senescence

Hodgkin's Lymphoma (HL) is one of the most prevailing malignancies in young adults. Reed–Sternberg (RS) cells in HL have distinctive large cell morphology, are characteristic of the disease and their presence is essential for diagnosis. Enlarged cells are one of the hallmarks of senescence, but...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gopas, J, Stern, E, Zurgil, U, Ozer, J, Ben-Ari, A, Shubinsky, G, Braiman, A, Sinay, R, Ezratty, J, Dronov, V, Balachandran, S, Benharroch, D, Livneh, E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287295/ https://www.ncbi.nlm.nih.gov/pubmed/27831553 http://dx.doi.org/10.1038/cddis.2016.185

Ejemplares similares

Primary Refractory and Relapsed Classical Hodgkin Lymphoma - Significance of Differential CD15 Expression in Hodgkin-Reed-Sternberg Cells
por: Benharroch, Daniel, et al.
Publicado: (2012)

CD20 Over-Expression in Hodgkin-Reed-Sternberg Cells of Classical Hodgkin Lymphoma: the Neglected Quest
por: Benharroch, Daniel, et al.
Publicado: (2015)

Hodgkin Reed–Sternberg-Like Cells in Non-Hodgkin Lymphoma
por: Parente, Paola, et al.
Publicado: (2020)

New molecular targets in Hodgkin and Reed-Sternberg cells
por: Sadaf, Hummaira, et al.
Publicado: (2023)

Reed Sternberg-Like Cells in Non-Hodgkin Lymphoma: A Diagnostic Challenge
por: Yadav, Geeta, et al.
Publicado: (2022)

p53 expression in Reed-Sternberg cells of Hodgkin's disease.
por: Gupta, R. K., et al.
Publicado: (1992)

Reed-Sternberg-like cells in follicular lymphoma
por: Son, Eun-mi, et al.
Publicado: (2014)

Reed-Sternberg and Hodgkin cells in bone marrow aspirate from a classical Hodgkin lymphoma patient
por: Oliveira, Leonardo Rodrigues, et al.
Publicado: (2022)

Loss of heterozygosity in the Hodgkin-Reed Sternberg cell line L1236
por: Staratschek-Jox, A, et al.
Publicado: (2001)

Characteristics of Sternberg-Reed, and related cells in Hodgkin's disease: an immunohistological study.
por: Dorreen, M. S., et al.
Publicado: (1984)

Interleukin 13 Is Secreted by and Stimulates the Growth of Hodgkin and Reed-Sternberg Cells
por: Kapp, Ursula, et al.
Publicado: (1999)

IMMUNOHISTOCHEMICAL DEMONSTRATION OF IgG IN REED-STERNBERG AND OTHER CELLS IN HODGKIN'S DISEASE
por: Garvin, A. J., et al.
Publicado: (1974)

Tackling the dysregulated immune-checkpoints in classical Hodgkin lymphoma: bidirectional regulations between the microenvironment and Hodgkin/Reed-Sternberg cells
por: Cellini, Alessandro, et al.
Publicado: (2023)

JAK/STAT blockade reverses the malignant phenotype of Hodgkin and Reed-Sternberg cells
por: Fernández, Sara, et al.
Publicado: (2022)

Basal autophagy is pivotal for Hodgkin and Reed-Sternberg cells' survival and growth revealing a new strategy for Hodgkin lymphoma treatment
por: Birkenmeier, Katrin, et al.
Publicado: (2016)

P038: HLA expression patterns of Hodgkin-Reed-Sternberg cells shape a spatially arranged tumor microenvironment in classical Hodgkin lymphoma
por: Müller-Meinhard, Berit, et al.
Publicado: (2022)

Genomic analyses of microdissected Hodgkin and Reed-Sternberg cells: mutations in epigenetic regulators and p53 are frequent in refractory classic Hodgkin lymphoma
por: Mata, Elena, et al.
Publicado: (2019)

The Prognostic Value of Eight Immunohistochemical Markers Expressed in the Tumor Microenvironment and on Hodgkin Reed-Sternberg Cells in Pediatric Patients With Classical Hodgkin Lymphoma
por: Zijtregtop, Eline A. M., et al.
Publicado: (2022)

Glycoproteomic characterization of carriers of the CD15/Lewis(x )epitope on Hodgkin's Reed-Sternberg cells
por: Powlesland, Alex S, et al.
Publicado: (2011)

Primary Cutaneous Follicle Centre Lymphoma with Hodgkin and Reed-Sternberg Like Cells: A Case Report and Review of the Literature
por: Aldarweesh, Fatima A., et al.
Publicado: (2017)

CD30 induces Reed‐Sternberg cell‐like morphology and chromosomal instability in classic Hodgkin lymphoma cell lines
por: Watanabe, Mariko, et al.
Publicado: (2023)

Matrix Metalloproteinase-9 Expression by Hodgkin-Reed-Sternberg Cells Is Associated with Reduced Overall Survival in Young Adult Patients with Classical Hodgkin Lymphoma
por: Campos, Antonio Hugo, et al.
Publicado: (2013)

c-FLIP Mediates Resistance of Hodgkin/Reed-Sternberg Cells to Death Receptor–induced Apoptosis
por: Mathas, Stephan, et al.
Publicado: (2004)

Ectopic CD137 expression facilitates the escape of Hodgkin and Reed-Sternberg cells from immunosurveillance
por: Pang, Wan Lu, et al.
Publicado: (2013)

100-year-old Haematologica images: Hodgkin and Reed-Sternberg cells in needle aspiration of the spleen
por: Balduini, Carlo L.
Publicado: (2020)

Chronic lymphocytic leukemia (CLL) with Reed–Sternberg-like cells vs Classic Hodgkin lymphoma transformation of CLL: does this distinction matter?
por: King, Rebecca L., et al.
Publicado: (2022)

P035: CRISPR/Cas9-mediated knockout reveals an important role of CD30 in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
por: Kilian, Annika L., et al.
Publicado: (2022)

Lymphangiogenesis in Classical Hodgkin Lymphoma - Preliminary Study with Clinicopathological Correlations
por: Benharroch, Daniel, et al.
Publicado: (2016)

Distinct 3D Structural Patterns of Lamin A/C Expression in Hodgkin and Reed-Sternberg Cells
por: Contu, Fabio, et al.
Publicado: (2018)

Development of a Bispecific Antibody Targeting CD30 and CD137 on Hodgkin and Reed-Sternberg Cells
por: Rajendran, Sakthi, et al.
Publicado: (2019)

Differences in Nuclear DNA Organization Between Lymphocytes, Hodgkin and Reed–Sternberg Cells Revealed by Structured Illumination Microscopy
por: Righolt, Christiaan H, et al.
Publicado: (2014)

Hodgkin-Reed-Sternberg Cells in Classical Hodgkin Lymphoma Show Alterations of Genes Encoding the NADPH Oxidase Complex and Impaired Reactive Oxygen Species Synthesis Capacity
por: Giefing, Maciej, et al.
Publicado: (2013)

The Reed-Sternberg cell/lymphocyte rosette. I. Properties of rosettes formed between Hodgkin's cell lines and allogeneic lymphocytes.
por: Flavell, D. J., et al.
Publicado: (1989)

Anomalous retinoblastoma protein expression in Sternberg-Reed cells in Hodgkin's disease: a comparative study with p53 and Ki67 expression.
por: Sánchez-Beato, M., et al.
Publicado: (1996)

The production of abnormal cells and Reed-Sternberg-like cells from normal lymphocytes.
por: Stuart, A. E.
Publicado: (1983)

Hodgkin and Reed-Sternberg cells in Hodgkin's disease represent the outgrowth of a dominant tumor clone derived from (crippled) germinal center B cells
Publicado: (1996)

Targeting Hodgkin and Reed–Sternberg Cells with an Inhibitor of Heat-Shock Protein 90: Molecular Pathways of Response and Potential Mechanisms of Resistance
por: Segges, Priscilla, et al.
Publicado: (2018)

Detection of Epstein‐Barr Virus DNA in Reed‐Sternberg Cells of Hodgkin's Disease Using the Polymerase Chain Reaction and in situ Hybridization
por: Uhara, Hisashi, et al.
Publicado: (1990)

Small and big Hodgkin-Reed-Sternberg cells of Hodgkin lymphoma cell lines L-428 and L-1236 lack consistent differences in gene expression profiles and are capable to reconstitute each other
por: Rengstl, Benjamin, et al.
Publicado: (2017)

Direct Detection of Epstein‐Barr Virus DNA from a Single Reed‐Sternberg Cell of Hodgkin's Disease by Polymerase Chain Reaction
por: Teramoto, Norihiro, et al.
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_3jq3pnsvtepk1f3u1ib8dj2pn0