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Preclinical evaluation of a chemically detoxified pneumolysin as pneumococcal vaccine antigen
The use of protein antigens able to protect against the majority of Streptococcus pneumoniae serotypes is envisaged as stand-alone and/or complement to the current capsular polysaccharide-based pneumococcal vaccines. Pneumolysin (Ply) is a key virulence factor that is highly conserved in amino acid...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287308/ https://www.ncbi.nlm.nih.gov/pubmed/27768518 http://dx.doi.org/10.1080/21645515.2016.1234553 |