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Preclinical evaluation of a chemically detoxified pneumolysin as pneumococcal vaccine antigen

The use of protein antigens able to protect against the majority of Streptococcus pneumoniae serotypes is envisaged as stand-alone and/or complement to the current capsular polysaccharide-based pneumococcal vaccines. Pneumolysin (Ply) is a key virulence factor that is highly conserved in amino acid...

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Detalles Bibliográficos
Autores principales:	Hermand, Philippe, Vandercammen, Annick, Mertens, Emmanuel, Di Paolo, Emmanuel, Verlant, Vincent, Denoël, Philippe, Godfroid, Fabrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287308/ https://www.ncbi.nlm.nih.gov/pubmed/27768518 http://dx.doi.org/10.1080/21645515.2016.1234553

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