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Metformin Impairs Spatial Memory and Visual Acuity in Old Male Mice

Metformin is an oral anti-diabetic used as first-line therapy for type 2 diabetes. Because benefits of metformin extend beyond diabetes to other age-related pathology, and because its effect on gene expression profiles resembles that of caloric restriction, metformin has a potential as an anti-aging...

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Detalles Bibliográficos
Autores principales: Thangthaeng, Nopporn, Rutledge, Margaret, Wong, Jessica M., Vann, Philip H., Forster, Michael J., Sumien, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287385/
https://www.ncbi.nlm.nih.gov/pubmed/28203479
http://dx.doi.org/10.14336/AD.2016.1010