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Metformin Impairs Spatial Memory and Visual Acuity in Old Male Mice
Metformin is an oral anti-diabetic used as first-line therapy for type 2 diabetes. Because benefits of metformin extend beyond diabetes to other age-related pathology, and because its effect on gene expression profiles resembles that of caloric restriction, metformin has a potential as an anti-aging...
Autores principales: | Thangthaeng, Nopporn, Rutledge, Margaret, Wong, Jessica M., Vann, Philip H., Forster, Michael J., Sumien, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287385/ https://www.ncbi.nlm.nih.gov/pubmed/28203479 http://dx.doi.org/10.14336/AD.2016.1010 |
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