Cargando…
Characterization of ADME gene variation in 21 populations by exome sequencing
OBJECTIVE: Proteins involving absorption, distribution, metabolism, and excretion (ADME) play a critical role in drug pharmacokinetics. The type and frequency of genetic variation in the ADME genes differ among populations. The aim of this study was to systematically investigate common and rare ADME...
Autores principales: | Hovelson, Daniel H., Xue, Zhengyu, Zawistowski, Matthew, Ehm, Margaret G., Harris, Elizabeth C., Stocker, Sophie L., Gross, Annette S., Jang, In-Jin, Ieiri, Ichiro, Lee, Jong-Eun, Cardon, Lon R., Chissoe, Stephanie L., Abecasis, Gonçalo, Nelson, Matthew R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287433/ https://www.ncbi.nlm.nih.gov/pubmed/27984508 http://dx.doi.org/10.1097/FPC.0000000000000260 |
Ejemplares similares
-
Comparing variant calling algorithms for target-exon sequencing in a large sample
por: Lo, Yancy, et al.
Publicado: (2015) -
The influence of genomic context on mutation patterns in the human genome inferred from rare variants
por: Schaibley, Valerie M., et al.
Publicado: (2013) -
Characterization of ADME Gene Variation in Colombian Population by Exome Sequencing
por: Silgado-Guzmán, Daniel Felipe, et al.
Publicado: (2022) -
Exome sequencing and complex disease: practical aspects of rare variant association studies
por: Do, Ron, et al.
Publicado: (2012) -
Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling
por: Chua, Eng Wee, et al.
Publicado: (2016)