BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency

Kaposi’s Sarcoma-associated Herpesvirus (KSHV) establishes stable latent infection in B-lymphocytes and pleural effusion lymphomas (PELs). During latency, the viral genome persists as an epigenetically constrained episome with restricted gene expression programs. To identify epigenetic regulators of...

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Detalles Bibliográficos
Autores principales: Chen, Horng-Shen, De Leo, Alessandra, Wang, Zhuo, Kerekovic, Andrew, Hills, Robert, Lieberman, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287475/
https://www.ncbi.nlm.nih.gov/pubmed/28107481
http://dx.doi.org/10.1371/journal.ppat.1006100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287475/
https://www.ncbi.nlm.nih.gov/pubmed/28107481
http://dx.doi.org/10.1371/journal.ppat.1006100

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