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Differential DNA Methylation Regions in Adult Human Sperm following Adolescent Chemotherapy: Potential for Epigenetic Inheritance

BACKGROUND: The potential that adolescent chemotherapy can impact the epigenetic programming of the germ line to influence later life adult fertility and promote epigenetic inheritance was investigated. Previous studies have demonstrated a number of environmental exposures such as abnormal nutrition...

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Detalles Bibliográficos
Autores principales: Shnorhavorian, Margarett, Schwartz, Stephen M., Stansfeld, Barbara, Sadler-Riggleman, Ingrid, Beck, Daniel, Skinner, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287489/
https://www.ncbi.nlm.nih.gov/pubmed/28146567
http://dx.doi.org/10.1371/journal.pone.0170085