Patients with CYP3A4∗1G genetic polymorphism consumed significantly lower amount of sufentanil in general anesthesia during lung resection

CYP3A4, an isoform of cytochrome P450 enzymes, is responsible for the metabolism of 45% to 60% of currently prescribed drugs. It has been shown that CYP3A4∗1G, a single nucleotide polymorphism (SNP), affects the enzymatic activity of CYP3A4. Sufentanil, a synthetic opioid commonly used for the induc...

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Detalles Bibliográficos
Autores principales: Zhang, Huidong, Chen, Minghao, Wang, Xiaodong, Yu, Songyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
3300
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287983/
https://www.ncbi.nlm.nih.gov/pubmed/28121959
http://dx.doi.org/10.1097/MD.0000000000006013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5287983/
https://www.ncbi.nlm.nih.gov/pubmed/28121959
http://dx.doi.org/10.1097/MD.0000000000006013

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