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In silico predicted structural and functional insights of all missense mutations on 2B domain of K1/K10 causing genodermatoses

The K1 and K10 associated genodermatoses are characterized by clinical symptoms of mild to severe redness, blistering and hypertrophy of the skin. In this paper, we set out to computationally investigate the structural and functional effects of missense mutations on the 2B domain of K1/K10 heterodim...

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Detalles Bibliográficos
Autores principales: Banerjee, Santasree, Wu, Qian, Ying, Yuyi, Li, Yanni, Shirota, Matsuyuki, Neculai, Dante, Li, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288147/
https://www.ncbi.nlm.nih.gov/pubmed/27421141
http://dx.doi.org/10.18632/oncotarget.10599