PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals

Platelet derived growth factor receptors (PDGFRs) play an important role in tumor pathogenesis, and they are frequently overexpressed in glioblastoma (GBM). Earlier we have shown a higher protein expression of PDGFR isoforms (α and β) in peritumoral-tissue derived cancer stem cells (p-CSC) than in t...

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Detalles Bibliográficos
Autores principales: Cenciarelli, Carlo, Marei, Hany E., Felsani, Armando, Casalbore, Patrizia, Sica, Gigliola, Puglisi, Maria Ausiliatrice, Cameron, Angus J.M., Olivi, Alessandro, Mangiola, Annunziato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288168/
https://www.ncbi.nlm.nih.gov/pubmed/27344175
http://dx.doi.org/10.18632/oncotarget.10132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288168/
https://www.ncbi.nlm.nih.gov/pubmed/27344175
http://dx.doi.org/10.18632/oncotarget.10132

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