COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia

IKZF1 deletion (ΔIKZF1) is an important predictor of relapse in childhood B-cell precursor acute lymphoblastic leukemia. Because of its clinical importance, we previously mapped breakpoints of intragenic deletions and developed a multiplex PCR assay to detect recurrent intragenic ΔIKZF1. Since the m...

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Detalles Bibliográficos
Autores principales: Lopes, Bruno Almeida, Meyer, Claus, Barbosa, Thayana Conceição, zur Stadt, Udo, Horstmann, Martin, Venn, Nicola C., Heatley, Susan, White, Deborah L., Sutton, Rosemary, Pombo-de-Oliveira, Maria S., Marschalek, Rolf, Emerenciano, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288169/
https://www.ncbi.nlm.nih.gov/pubmed/27419633
http://dx.doi.org/10.18632/oncotarget.10590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288169/
https://www.ncbi.nlm.nih.gov/pubmed/27419633
http://dx.doi.org/10.18632/oncotarget.10590

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