Cargando…
COBL is a novel hotspot for IKZF1 deletions in childhood acute lymphoblastic leukemia
IKZF1 deletion (ΔIKZF1) is an important predictor of relapse in childhood B-cell precursor acute lymphoblastic leukemia. Because of its clinical importance, we previously mapped breakpoints of intragenic deletions and developed a multiplex PCR assay to detect recurrent intragenic ΔIKZF1. Since the m...
Autores principales: | Lopes, Bruno Almeida, Meyer, Claus, Barbosa, Thayana Conceição, zur Stadt, Udo, Horstmann, Martin, Venn, Nicola C., Heatley, Susan, White, Deborah L., Sutton, Rosemary, Pombo-de-Oliveira, Maria S., Marschalek, Rolf, Emerenciano, Mariana |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288169/ https://www.ncbi.nlm.nih.gov/pubmed/27419633 http://dx.doi.org/10.18632/oncotarget.10590 |
Ejemplares similares
-
IKZF1 Deletions with COBL Breakpoints Are Not Driven by RAG-Mediated Recombination Events in Acute Lymphoblastic Leukemia
por: Lopes, Bruno A., et al.
Publicado: (2019) -
P337: IKZF1 DELETIONS IN B-ALL: FROM ITS GENETIC BASIS TO DIAGNOSTIC ENHANCEMENT
por: Lopes, Bruno A., et al.
Publicado: (2023) -
IKZF1 deletions associate with CRLF2 overexpression leading to a poor prognosis in B-cell precursor acute lymphoblastic leukaemia
por: Maciel, Ana Luiza Tardem, et al.
Publicado: (2021) -
ARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia
por: Emerenciano, Mariana, et al.
Publicado: (2014) -
Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development
por: Izadi, Maryam, et al.
Publicado: (2021)