KRAS(G12) mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway

It remains unclear how the signals of mutant KRAS(G12) in the transformed cells spread to the surrounding non-mutated cells and changes the microenvironment to promote tumor formation. We identified that Williams–Beuren syndrome transcription factor (WSTF), a non-secretory protein, was released in c...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Wang, Shu-Qing, Long, Yue-Hong, Chen, Su, Li, Yu-Feng, Zhang, Jing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288175/
https://www.ncbi.nlm.nih.gov/pubmed/27449290
http://dx.doi.org/10.18632/oncotarget.10625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288175/
https://www.ncbi.nlm.nih.gov/pubmed/27449290
http://dx.doi.org/10.18632/oncotarget.10625

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