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KRAS(G12) mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway
It remains unclear how the signals of mutant KRAS(G12) in the transformed cells spread to the surrounding non-mutated cells and changes the microenvironment to promote tumor formation. We identified that Williams–Beuren syndrome transcription factor (WSTF), a non-secretory protein, was released in c...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288175/ https://www.ncbi.nlm.nih.gov/pubmed/27449290 http://dx.doi.org/10.18632/oncotarget.10625 |