CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin

Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that are a major cause of mortality of Neurofibromatosis type 1 (NF1) patients. MPNST patients have few therapeutic options available and only complete surgical resection can be curative. MPNST formation and survival are depe...

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Detalles Bibliográficos
Autores principales: Kendall, Jed J., Chaney, Katherine E., Patel, Ami V., Rizvi, Tilat A., Largaespada, David A., Ratner, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288178/
https://www.ncbi.nlm.nih.gov/pubmed/27448963
http://dx.doi.org/10.18632/oncotarget.10668

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288178/
https://www.ncbi.nlm.nih.gov/pubmed/27448963
http://dx.doi.org/10.18632/oncotarget.10668

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