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CK2 blockade causes MPNST cell apoptosis and promotes degradation of β-catenin
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that are a major cause of mortality of Neurofibromatosis type 1 (NF1) patients. MPNST patients have few therapeutic options available and only complete surgical resection can be curative. MPNST formation and survival are depe...
Autores principales: | Kendall, Jed J., Chaney, Katherine E., Patel, Ami V., Rizvi, Tilat A., Largaespada, David A., Ratner, Nancy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288178/ https://www.ncbi.nlm.nih.gov/pubmed/27448963 http://dx.doi.org/10.18632/oncotarget.10668 |
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