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Radiation driven epithelial-mesenchymal transition is mediated by Notch signaling in breast cancer

Epithelial to mesenchymal transition (EMT) is developmental process associated with cancer metastasis. Here, we found that breast carcinoma cells adopt epithelial-to-mesenchymal transition (EMT) in response to fractionated-radiation. Importantly, we show that Notch signaling is highly activated in f...

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Detalles Bibliográficos
Autores principales: Kim, Rae-Kwon, Kaushik, Neha, Suh, Yongjoon, Yoo, Ki-Chun, Cui, Yan-Hong, Kim, Min-Jung, Lee, Hae-June, Kim, In-Gyu, Lee, Su-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288197/
https://www.ncbi.nlm.nih.gov/pubmed/27462787
http://dx.doi.org/10.18632/oncotarget.10802