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Crosstalk among the proteome, lysine phosphorylation, and acetylation in romidepsin-treated colon cancer cells

Romidepsin (FK228) is one of the most promising histone-deacetylase inhibitors due to its potent antitumor activity, and has been used as a practical option for cancer therapy. However, FK228-induced changes in protein modifications and the crosstalk between different modifications has not been repo...

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Detalles Bibliográficos
Autores principales: Wang, Tian-Yun, Chai, Yu-Rong, Jia, Yan-Long, Gao, Jian-Hui, Peng, Xiao-Jun, Han, Hua-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288200/
https://www.ncbi.nlm.nih.gov/pubmed/27472459
http://dx.doi.org/10.18632/oncotarget.10840