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Hypoxia inducible factor-1α regulates a pro-invasive phenotype in acute monocytic leukemia
Hypoxia inducible transcription factors (HIFs) are the main regulators of adaptive responses to hypoxia and are often activated in solid tumors, but their role in leukemia is less clear. In acute myeloid leukemia (AML), in particular, controversial new findings indicate that HIF-1α can act either as...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288204/ https://www.ncbi.nlm.nih.gov/pubmed/27447550 http://dx.doi.org/10.18632/oncotarget.10660 |