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Hypoxia inducible factor-1α regulates a pro-invasive phenotype in acute monocytic leukemia

Hypoxia inducible transcription factors (HIFs) are the main regulators of adaptive responses to hypoxia and are often activated in solid tumors, but their role in leukemia is less clear. In acute myeloid leukemia (AML), in particular, controversial new findings indicate that HIF-1α can act either as...

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Detalles Bibliográficos
Autores principales: Migliavacca, Jessica, Percio, Stefano, Valsecchi, Roberta, Ferrero, Elisabetta, Spinelli, Antonello, Ponzoni, Maurilio, Tresoldi, Cristina, Pattini, Linda, Bernardi, Rosa, Coltella, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288204/
https://www.ncbi.nlm.nih.gov/pubmed/27447550
http://dx.doi.org/10.18632/oncotarget.10660