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miR-7 reverses the resistance to BRAFi in melanoma by targeting EGFR/IGF-1R/CRAF and inhibiting the MAPK and PI3K/AKT signaling pathways

MicroRNAs (miRNAs) are attractive therapeutic targets for various therapy-resistant tumors. However, the association between miRNA and BRAF inhibitor resistance in melanoma remains to be elucidated. We used microarray analysis to comprehensively study the miRNA expression profiling of vemurafenib re...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoyan, Li, Jun, Sun, Yanhong, Zhang, Yi, Dong, Liyun, Shen, Chen, Yang, Liu, Yang, Ming, Li, Yan, Shen, Guanxin, Tu, Yating, Tao, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288205/
https://www.ncbi.nlm.nih.gov/pubmed/27448964
http://dx.doi.org/10.18632/oncotarget.10669