miR-28 modulates exhaustive differentiation of T cells through silencing programmed cell death-1 and regulating cytokine secretion

T cell exhaustion is a state of T cell dysfunction that arises during many cancer. miRNAs are one of major gene regulators which result in translational inhibition and/or mRNA degradation. We hypothesized that miRNAs exist that can silence PD1 and act as a modulator in vitro to revert exhaustive sta...

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Detalles Bibliográficos
Autores principales: Li, Qing, Johnston, Nathan, Zheng, Xiufen, Wang, Hongmei, Zhang, Xusheng, Gao, Dian, Min, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288217/
https://www.ncbi.nlm.nih.gov/pubmed/27447564
http://dx.doi.org/10.18632/oncotarget.10731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288217/
https://www.ncbi.nlm.nih.gov/pubmed/27447564
http://dx.doi.org/10.18632/oncotarget.10731

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