A Novel Slug-containing Negative Feedback Loop regulates SCF/c-Kit-Mediated Hematopoietic Stem Cell Self-renewal

The SCF/c-Kit pathway has crucial roles in controlling hematopoietic stem cell (HSC) renewal. However, little is known about the intracellular regulation of the SCF/c-Kit pathway in HSCs. We report here that Slug, a zinc-finger transcription repressor, functions as a direct transcriptional repressor...

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Detalles Bibliográficos
Autores principales: Zhang, Zhonghui, Zhu, Pei, Zhou, Yalu, Sheng, Yue, Hong, Yuanfan, Xiang, Di, Qian, Zhijian, Mosenson, Jeffrey, Wu, Wen-Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288275/
https://www.ncbi.nlm.nih.gov/pubmed/27451973
http://dx.doi.org/10.1038/leu.2016.201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288275/
https://www.ncbi.nlm.nih.gov/pubmed/27451973
http://dx.doi.org/10.1038/leu.2016.201

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