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Clinical Impact of Minimal Residual Disease in Children with Different Subtypes of Acute Lymphoblastic Leukemia Treated with Response-Adapted Therapy

To determine the clinical significance of minimal residual disease (MRD) in patients with prognostically relevant subtypes of childhood acute lymphoblastic leukemia (ALL), we analyzed data from 488 patients treated in St. Jude Total Therapy Study XV with treatment intensity based mainly on MRD level...

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Detalles Bibliográficos
Autores principales: Pui, Ching-Hon, Pei, Deqing, Raimondi, Susana C, Coustan-Smith, Elaine, Jeha, Sima, Cheng, Cheng, Bowman, W Paul, Sandlund, John T, Ribeiro, Raul C, Rubnitz, Jeffrey E, Inaba, Hiroto, Gruber, Tanja A, Leung, Wing H, Yang, Jun J, Downing, James R, Evans, William E, Relling, Mary V, Campana, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288281/
https://www.ncbi.nlm.nih.gov/pubmed/27560110
http://dx.doi.org/10.1038/leu.2016.234