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A Paradigm Shift on the Question of B Cells in Transplantation? Recent Insights on Regulating the Alloresponse

B lymphocytes contribute to acute and chronic allograft rejection through their production of donor-specific antibodies (DSAs). In addition, B cells present allopeptides bound to self-MHC class II molecules and provide costimulation signals to T cells, which are essential to their activation and dif...

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Detalles Bibliográficos
Autores principales: Firl, Daniel J., Benichou, Gilles, Kim, James I., Yeh, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288351/
https://www.ncbi.nlm.nih.gov/pubmed/28210263
http://dx.doi.org/10.3389/fimmu.2017.00080