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A Paradigm Shift on the Question of B Cells in Transplantation? Recent Insights on Regulating the Alloresponse
B lymphocytes contribute to acute and chronic allograft rejection through their production of donor-specific antibodies (DSAs). In addition, B cells present allopeptides bound to self-MHC class II molecules and provide costimulation signals to T cells, which are essential to their activation and dif...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288351/ https://www.ncbi.nlm.nih.gov/pubmed/28210263 http://dx.doi.org/10.3389/fimmu.2017.00080 |