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APP as a Protective Factor in Acute Neuronal Insults

Despite its key role in the molecular pathology of Alzheimer’s disease (AD), the physiological function of amyloid precursor protein (APP) is unknown. Increasing evidence, however, points towards a neuroprotective role of this membrane protein in situations of metabolic stress. A key observation is...

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Detalles Bibliográficos
Autores principales: Hefter, Dimitri, Draguhn, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288400/
https://www.ncbi.nlm.nih.gov/pubmed/28210211
http://dx.doi.org/10.3389/fnmol.2017.00022