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Sirtuins Expression and Their Role in Retinal Diseases

Sirtuins have received considerable attention since the discovery that silent information regulator 2 (Sir2) extends the lifespan of yeast. Sir2, a nicotinamide adenine dinucleotide- (NAD-) dependent histone deacetylase, serves as both a transcriptional effector and energy sensor. Oxidative stress a...

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Detalles Bibliográficos
Autores principales: Balaiya, Sankarathi, Abu-Amero, Khaled K., Kondkar, Altaf A., Chalam, Kakarla V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288547/
https://www.ncbi.nlm.nih.gov/pubmed/28197299
http://dx.doi.org/10.1155/2017/3187594