Weight and Body Composition Compartments do Not Predict Therapeutic Thiopurine Metabolite Levels in Inflammatory Bowel Disease

OBJECTIVES: Thiopurine drugs are the most commonly used steroid-sparing therapies in moderate-to-severe inflammatory bowel disease (IBD). Their complex metabolism and their narrow therapeutic windows means that optimal dosing is difficult. However, weight-based dosing is the norm. Similar antimetabo...

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Detalles Bibliográficos
Autores principales: Holt, Darcy Q, Strauss, Boyd JG, Moore, Gregory T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288590/
https://www.ncbi.nlm.nih.gov/pubmed/27787512
http://dx.doi.org/10.1038/ctg.2016.56

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288590/
https://www.ncbi.nlm.nih.gov/pubmed/27787512
http://dx.doi.org/10.1038/ctg.2016.56

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