Intein-mediated backbone cyclization of VP1 protein enhanced protection of CVB3-induced viral myocarditis

CVB3 is a common human pathogen to be highly lethal to newborns and causes viral myocarditis and pancreatitis in adults. However, there is no vaccine available for clinical use. CVB3 capsid protein VP1 is an immunodominant structural protein, containing several B- and T-cell epitopes. However, immun...

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Detalles Bibliográficos
Autores principales: Qi, Xingmei, Xiong, Sidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288654/
https://www.ncbi.nlm.nih.gov/pubmed/28148910
http://dx.doi.org/10.1038/srep41485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288654/
https://www.ncbi.nlm.nih.gov/pubmed/28148910
http://dx.doi.org/10.1038/srep41485

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