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Intein-mediated backbone cyclization of VP1 protein enhanced protection of CVB3-induced viral myocarditis
CVB3 is a common human pathogen to be highly lethal to newborns and causes viral myocarditis and pancreatitis in adults. However, there is no vaccine available for clinical use. CVB3 capsid protein VP1 is an immunodominant structural protein, containing several B- and T-cell epitopes. However, immun...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288654/ https://www.ncbi.nlm.nih.gov/pubmed/28148910 http://dx.doi.org/10.1038/srep41485 |