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MISTIC-fusion proteins as antigens for high quality membrane protein antibodies

Lack of high-quality antibodies against transmembrane proteins is a widely recognized hindrance in biomedical and cell biological research. Here we present a robust pipeline for the generation of polyclonal antibodies employing full-length membrane proteins as immunogens to overcome this “antibody b...

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Detalles Bibliográficos
Autores principales: Alves, Natalia Silva, Astrinidis, Susanne Adina, Eisenhardt, Nathalie, Sieverding, Cornelia, Redolfi, Josef, Lorenz, Michael, Weberruss, Marion, Moreno-Andrés, Daniel, Antonin, Wolfram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288655/
https://www.ncbi.nlm.nih.gov/pubmed/28148968
http://dx.doi.org/10.1038/srep41519