Construction of a guide-RNA for site-directed RNA mutagenesis utilising intracellular A-to-I RNA editing

As an alternative to DNA mutagenesis, RNA mutagenesis can potentially become a powerful gene-regulation method for fundamental research and applied life sciences. Adenosine-to-inosine (A-to-I) RNA editing alters genetic information at the transcript level and is an important biological process that...

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Detalles Bibliográficos
Autores principales: Fukuda, Masatora, Umeno, Hiromitsu, Nose, Kanako, Nishitarumizu, Azusa, Noguchi, Ryoma, Nakagawa, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288656/
https://www.ncbi.nlm.nih.gov/pubmed/28148949
http://dx.doi.org/10.1038/srep41478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288656/
https://www.ncbi.nlm.nih.gov/pubmed/28148949
http://dx.doi.org/10.1038/srep41478

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