Cargando…

Construction of a guide-RNA for site-directed RNA mutagenesis utilising intracellular A-to-I RNA editing

As an alternative to DNA mutagenesis, RNA mutagenesis can potentially become a powerful gene-regulation method for fundamental research and applied life sciences. Adenosine-to-inosine (A-to-I) RNA editing alters genetic information at the transcript level and is an important biological process that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fukuda, Masatora, Umeno, Hiromitsu, Nose, Kanako, Nishitarumizu, Azusa, Noguchi, Ryoma, Nakagawa, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288656/ https://www.ncbi.nlm.nih.gov/pubmed/28148949 http://dx.doi.org/10.1038/srep41478

Ejemplares similares

Improved design of hammerhead ribozyme for selective digestion of target RNA through recognition of site-specific adenosine-to-inosine RNA editing
por: Fukuda, Masatora, et al.
Publicado: (2014)

Regulation of RNA editing by intracellular acidification
por: Malik, Turnee N, et al.
Publicado: (2021)

RNA-based cooperative protein labeling that permits direct monitoring of the intracellular concentration change of an endogenous protein
por: Pe, Kathleen Beverly Alog, et al.
Publicado: (2021)

Learning cis-regulatory principles of ADAR-based RNA editing from CRISPR-mediated mutagenesis
por: Liu, Xin, et al.
Publicado: (2021)

Host A-to-I RNA editing signatures in intracellular bacterial and single-strand RNA viral infections
por: Wei, Zhi-Yuan, et al.
Publicado: (2023)

Deletions in cox2 mRNA Result in Loss of Splicing and RNA Editing and Gain of Novel RNA Editing Sites
por: Grüttner, Stefanie, et al.
Publicado: (2013)

Construction of therapeutically relevant human prostate epithelial fate map by utilising miRNA and mRNA microarray expression data
por: Rane, Jayant K, et al.
Publicado: (2015)

C-to-U RNA Editing: A Site Directed RNA Editing Tool for Restoration of Genetic Code
por: Bhakta, Sonali, et al.
Publicado: (2022)

Functional Validation of cas9/GuideRNA Constructs for Site-Directed Mutagenesis of Triticale ABA8′OH1 loci
por: Michalski, Krzysztof, et al.
Publicado: (2021)

1-Deazaguanosine-Modified RNA: The Missing Piece for Functional RNA Atomic Mutagenesis
por: Bereiter, Raphael, et al.
Publicado: (2022)

Identification of RNA editing sites in the SNP database
por: Eisenberg, Eli, et al.
Publicado: (2005)

iRNA-AI: identifying the adenosine to inosine editing sites in RNA sequences
por: Chen, Wei, et al.
Publicado: (2016)

Investigation of RNA Editing Sites within Bound Regions of RNA-Binding Proteins
por: Weirick, Tyler, et al.
Publicado: (2019)

L-GIREMI uncovers RNA editing sites in long-read RNA-seq
por: Liu, Zhiheng, et al.
Publicado: (2023)

RNA editing: Expanding the potential of RNA therapeutics
por: Booth, Brian J., et al.
Publicado: (2023)

Mitochondrial Genome Evolution and a Novel RNA Editing System in Deep-Branching Heteroloboseids
por: Yang, Jiwon, et al.
Publicado: (2017)

Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR
por: Tohama, Tetsuto, et al.
Publicado: (2020)

Engineering Novel Molecular Beacon Constructs to Study Intracellular RNA Dynamics and Localization
por: Ma, Zhao, et al.
Publicado: (2017)

RNA mutagenesis yields highly diverse mRNA libraries for in vitro protein evolution
por: Kopsidas, George, et al.
Publicado: (2007)

Nascent RNA folding mitigates transcription-associated mutagenesis
por: Chen, Xiaoshu, et al.
Publicado: (2016)

Pentatricopeptide repeat proteins involved in plant organellar RNA editing
por: Yagi, Yusuke, et al.
Publicado: (2013)

RNA editing in nascent RNA affects pre-mRNA splicing
por: Hsiao, Yun-Hua Esther, et al.
Publicado: (2018)

RNA editing in the human ENCODE RNA-seq data
por: Park, Eddie, et al.
Publicado: (2012)

RCARE: RNA Sequence Comparison and Annotation for RNA Editing
por: Lee, Soo Youn, et al.
Publicado: (2015)

Predicting sites of ADAR editing in double-stranded RNA
por: Eggington, Julie M., et al.
Publicado: (2011)

Genome Sequence-Independent Identification of RNA Editing Sites
por: Zhang, Qing, et al.
Publicado: (2015)

Regulatory RNA Editing Sites in Cancer: Prediction and Beyond
por: Ruan, Hang, et al.
Publicado: (2017)

Genome-wide profiling of RNA editing sites in sheep
por: Zhang, Yuanyuan, et al.
Publicado: (2019)

The Impact of mRNA Structure on Guide RNA Targeting in Kinetoplastid RNA Editing
por: Reifur, Larissa, et al.
Publicado: (2010)

REDIdb: the RNA editing database
por: Picardi, Ernesto, et al.
Publicado: (2007)

Repetitive Editing and RNA Splicing
Publicado: (2004)

RNA Editing and Retrotransposons in Neurology
por: Krestel, Heinz, et al.
Publicado: (2018)

RNA-editing in Basidiomycota, revisited
por: Min, Byoungnam, et al.
Publicado: (2021)

RNA Editing in Cancer Progression
por: Frezza, Valentina, et al.
Publicado: (2023)

Intracellular RNA-tracking methods
por: George, Logan, et al.
Publicado: (2018)

Determinants for tRNA-Dependent Pretransfer Editing in the Synthetic Site of Isoleucyl-tRNA Synthetase
por: Dulic, Morana, et al.
Publicado: (2014)

Repair of CRISPR-guided RNA breaks enables site-specific RNA editing in human cells
por: Nemudraia, Anna, et al.
Publicado: (2023)

Lethal mutagenesis of an RNA plant virus via lethal defection
por: Díaz-Martínez, Luis, et al.
Publicado: (2018)

A synthetic RNA editing factor edits its target site in chloroplasts and bacteria
por: Royan, Santana, et al.
Publicado: (2021)

RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA
por: Cui, Yalei, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_k73fkuk41nipaubfp8pm8cah8f