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Exosome-Based Delivery of miR-124 in a Huntington’s Disease Model

OBJECTIVE: Huntington’s disease (HD) is a genetic neurodegenerative disease that is caused by abnormal CAG expansion. Altered microRNA (miRNA) expression also causes abnormal gene regulation in this neurodegenerative disease. The delivery of abnormally downregulated miRNAs might restore normal gene...

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Detalles Bibliográficos
Autores principales: Lee, Soon-Tae, Im, Wooseok, Ban, Jae-Jun, Lee, Mijung, Jung, Keun-Hwa, Lee, Sang Kun, Chu, Kon, Kim, Manho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Movement Disorder Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288667/
https://www.ncbi.nlm.nih.gov/pubmed/28122430
http://dx.doi.org/10.14802/jmd.16054