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Puzzles in modern biology. IV. Neurodegeneration, localized origin and widespread decay

The motor neuron disease amyotrophic lateral sclerosis (ALS) typically begins with localized muscle weakness. Progressive, widespread paralysis often follows over a few years. Does the disease begin with local changes in a small piece of neural tissue and then spread? Or does neural decay happen ind...

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Detalles Bibliográficos
Autor principal: Frank, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288670/
https://www.ncbi.nlm.nih.gov/pubmed/28184284
http://dx.doi.org/10.12688/f1000research.9790.1