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An Engineered Herpesvirus Activates Dendritic Cells and Induces Protective Immunity
Herpes simplex viruses (HSV) are human pathogens that switch between lytic and latent infection. While attenuated HSV is explored for vaccine, the underlying event remains poorly defined. Here we report that recombinant HSV-1 with a mutation in the γ(1)34.5 protein, a virulence factor, stimulates de...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288694/ https://www.ncbi.nlm.nih.gov/pubmed/28150813 http://dx.doi.org/10.1038/srep41461 |