Bioengineering a bacterial pathogen to assemble its own particulate vaccine capable of inducing cellular immunity

Many bacterial pathogens naturally form cellular inclusions. Here the immunogenicity of polyhydroxyalkanoate (PHA) inclusions and their use as particulate vaccines delivering a range of host derived antigens was assessed. Our study showed that PHA inclusions of pathogenic Pseudomonas aeruginosa are...

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Detalles Bibliográficos
Autores principales: Lee, Jason W., Parlane, Natalie A., Wedlock, D. Neil, Rehm, Bernd H. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288705/
https://www.ncbi.nlm.nih.gov/pubmed/28150705
http://dx.doi.org/10.1038/srep41607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288705/
https://www.ncbi.nlm.nih.gov/pubmed/28150705
http://dx.doi.org/10.1038/srep41607

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