Cellular prion protein is present in mitochondria of healthy mice

Cellular prion protein (PrP(C)) is a mammalian glycoprotein which is usually found anchored to the plasma membrane via a glycophosphatidylinositol (GPI) anchor. PrP(C) misfolds to a pathogenic isoform PrP(Sc), the causative agent of neurodegenerative prion diseases. The precise function of PrP(C) re...

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Detalles Bibliográficos
Autores principales: Faris, Robert, Moore, Roger A., Ward, Anne, Race, Brent, Dorward, David W., Hollister, Jason R., Fischer, Elizabeth R., Priola, Suzette A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288712/
https://www.ncbi.nlm.nih.gov/pubmed/28148964
http://dx.doi.org/10.1038/srep41556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288712/
https://www.ncbi.nlm.nih.gov/pubmed/28148964
http://dx.doi.org/10.1038/srep41556

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