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Cellular prion protein is present in mitochondria of healthy mice
Cellular prion protein (PrP(C)) is a mammalian glycoprotein which is usually found anchored to the plasma membrane via a glycophosphatidylinositol (GPI) anchor. PrP(C) misfolds to a pathogenic isoform PrP(Sc), the causative agent of neurodegenerative prion diseases. The precise function of PrP(C) re...
Autores principales: | Faris, Robert, Moore, Roger A., Ward, Anne, Race, Brent, Dorward, David W., Hollister, Jason R., Fischer, Elizabeth R., Priola, Suzette A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288712/ https://www.ncbi.nlm.nih.gov/pubmed/28148964 http://dx.doi.org/10.1038/srep41556 |
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