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Discovering missing reactions of metabolic networks by using gene co-expression data

Flux coupling analysis is a computational method which is able to explain co-expression of metabolic genes by analyzing the topological structure of a metabolic network. It has been suggested that if genes in two seemingly fully-coupled reactions are not highly co-expressed, then these two reactions...

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Detalles Bibliográficos
Autores principales: Hosseini, Zhaleh, Marashi, Sayed-Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288723/
https://www.ncbi.nlm.nih.gov/pubmed/28150713
http://dx.doi.org/10.1038/srep41774